We've long known that the ability to laugh is helpful to those coping with major illness and the stress of life's problems. But researchers are now saying laughter can do a lot more -- it can basically bring balance to all the components of the immune system, which helps us fight off diseases. (See How the Immune System Works.)
As we mentioned earlier, laughter reduces levels of certain stress hormones. In doing this, laughter provides a safety valve that shuts off the flow of stress hormones and the fight-or-flight compounds that swing into action in our bodies when we experience stress, anger or hostility. These stress hormones suppress the immune system, increase the number of blood platelets (which can cause obstructions in arteries) and raise blood pressure. When we're laughing, natural killer cells that destroy tumors and viruses increase, as do Gamma-interferon (a disease-fighting protein), T-cells, which are a major part of the immune response, and B-cells, which make disease-destroying antibodies.
Laughter may lead to hiccuping and coughing, which clears the respiratory tract by dislodging mucous plugs. Laughter also increases the concentration of salivary immunoglobulin A, which defends against infectious