第二部分：英语知识运用(共两节，满分35分)
第一节：单项填空(共15小题；每小题1分，满分15分)
从A、B、C、D四个选项中，选出可填入空白处的最佳选项。
21. _______ the beginning of 1999, the popularity of MP3 has increased greatly.
A. In B. Since C. To D. At
22. Shanghai is among the largest cities across the world _______ its size and population.
A. in place of B. in case of C. in terms of D. in control of
